In-line mini-environment contamination detection and monitoring system

An apparatus comprising:

• an active flow control system including one or more inlets and one or more outlets, wherein:
• a first outlet of the one or more outlets is configured to be fluidly coupled to an inlet of a mini-environment, and
• a first inlet of the one or more inlets is configured to be coupled to an outlet of the mini-environment;
• and
• wherein the active flow control system includes one or more flow control configurations, wherein each flow control configuration corresponds to a flow control modes, the one or more flow configurations including a configuration corresponding to a sampling mode comprising:
• injecting a neutral fluid from the first outlet into the inlet of the mini-environment, and
• directing a mixed fluid exiting through the outlet of the mini-environment to the first inlet of the active flow control system, the mixed fluid being a combination of the neutral fluid and the fluid that was in the mini-environment before injecting the neutral fluid into the mini-environment.