Glycan age prediction model
AssigneeThe Regents of the University of California
InventorsEmanual Maverakis, Alexander Merleev, Carlito Lebrilla
Life of this patent
Estimating the term…
Abstract
Provided herein are methods for determining the age of a subject by measuring the relative abundance of glycopeptides (e.g., using mass spectrometry) in a biological sample from the subject. Also provided are methods for comparing the relative abundance of the glycopeptides to age prediction models to determine the age of the subject. The age prediction models provided herein are based on the relative abundance of the glycopeptides in control populations.
Claims20
A method for determining the age of a biological sample from a subject, the method comprising measuring a relative abundance of at least one glycopeptide in the biological sample and comparing the relative abundance of the at least one glycopeptide to an age prediction model, wherein the age prediction model comprises the relative abundance of the at least one glycopeptide in at least one control biological sample, wherein each control biological sample is from a control individual of a known age, thereby determining the age of the biological sample.
Dependencies are inferred from the claim text.