Biomarkers for colorectal cancer
AssigneeVision Tech Bio Pty Ltd
InventorsTrevor LOCKETT, Eduardo VOM, Craig LEWIS, Michael BUCKLEY, Louise MILLER, Christian DAISH
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Abstract
The present invention relates to the identification of biomarkers which are associated with a higher risk of advanced colorectal Neoplasia (ACN), for example colorectal cancer (CRC), in a subject. The detection and measurement of these biomarkers in a biological sample may be used to inform the clinician as to whether further invasive procedures including colonoscopy or sigmoidoscopy are required to provide a definitive diagnosis of colorectal cancer in the subject.
Claims21
A method for identifying a subject suspected of having colorectal cancer, the method comprising:
- determining a measurement for a panel of biomarkers in a biological sample obtained from the subject, the panel comprising at least brain derived neurotropic factor (BDNF) and tumour M2-PK;
- wherein the measurement comprises measuring a level of each of the biomarkers in the panel.
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Dependencies are inferred from the claim text.