Staufen1 regulating agents and associated methods
AssigneeUniversity of Utah Research Foundation
InventorsStefan M. Pulst, Daniel R. Scoles, Sharan Paul
Life of this patent
Estimating the term…
Abstract
Methods of minimizing dysregulation of Staufen1-associated RNA metabolism can include introducing an amount of a Staufen1-regulating agent to a target cell sufficient to minimize the dysregulation. Therapeutic compositions for treating a neurodegenerative condition associated with Staufen1-induced dysregulation of RNA metabolism can include a therapeutically effective amount of a Staufen1-regulating agent and a pharmaceutically acceptable carrier.
Claims20
A method of treating a neurological condition associated with a mutation of the C9orf72 gene, the TDP-43 gene, the HTT gene, the PSEN1 gene, the MAPT gene, or a combination thereof, comprising:
- introducing an amount of a Staufen1-regulating agent to a target cell that is sufficient to minimize Staufen1-induced dysregulation of RNA metabolism.
Dependencies are inferred from the claim text.