Pharmaceutical combination for use in age-related and/or degenerative diseases
AssigneeRejuvenate Biomed
InventorAnn Beliën
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Abstract
The present invention relates to a pharmaceutical combination for use in the treatment, prevention and/or stabilization of age-related diseases and/or degenerative diseases. In particular, said pharmaceutical combination comprises a biguanide and an acetylcholinesterase inhibitor and/or an N-oxide, a hydrate, a pharmaceutically acceptable salt or solvate thereof. The invention is further also directed to the use of said pharmaceutical combination for prevention, stabilization and/or reduction of age-related complaints and/or degenerative complaints; and for improving a measure of life span and/or health span.
Claims14
A method for treating frailty, the method comprising:
- administering to a subject in need thereof a pharmaceutical combination comprising:
- a biguanide, or an N-oxide, a hydrate, a pharmaceutically acceptable salt or solvate thereof;
- and
- an acetylcholinesterase inhibitor, or an N-oxide, a hydrate, a pharmaceutically acceptable salt or solvate thereof.
A method for improving a measure of life span and/or health span in a subject suffering from frailty, the method comprising:
- administering to a subject a pharmaceutical combination comprising:
- a biguanide, or an N-oxide, a hydrate, a pharmaceutically acceptable salt or solvate thereof;
- and
- an acetylcholinesterase inhibitor, or an N-oxide, a hydrate, a pharmaceutically acceptable salt or solvate thereof,
- wherein the improved measure of life span and/or health span is the lessening or reduction in the severity of at least one clinical symptom associated with frailty.
Dependencies are inferred from the claim text.