Medical device delivery systems

A medical device delivery system comprising:

• a steerable catheter defining a first lumen;
• a pull wire comprising a distal end coupled to a distal end portion of the steerable catheter;
• a balloon catheter slidably disposed within the first lumen and comprising an inflatable balloon member at a distal end portion thereof;
• and
• a handle device comprising:
• a housing;
• a first rotatable actuator knob rotatably coupled to the housing and comprising a sleeve with an internal thread;
• a traveler guide shaft extending internally within the sleeve, wherein a proximal end of the steerable catheter is affixed to the traveler guide;
• a deflection nut with an external thread in engagement with the internal thread of the sleeve and defining a bore with a non-circular cross-section in which the traveler guide slidably extends, wherein a proximal end of the pull wire is coupled with the deflection nut;
• a balloon catheter pull rod extending proximally from the housing, wherein a proximal end of the balloon catheter is affixed to the balloon catheter pull rod;
• a locking mechanism rotatably coupled to the housing and manually adjustable between a locked position and an unlocked position, wherein the locking mechanism is configured to releasably detain the balloon catheter in relation to the housing when the locking mechanism is in the locked position;
• and
• a second rotatable actuator knob rotatably coupled to the housing and configured to rotate the balloon catheter pull rod and the balloon catheter while allowing the balloon catheter pull rod to longitudinally translate in relation to the second rotatable actuator knob when the locking mechanism is in the unlocked position.