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US 2024/0389937 A1Published application
Systems and methods for treating cancer and/or augmenting organ function
AssigneeAutonomix Medical, Inc.
InventorsLandy Toth, Robert S. Schwartz
Life of this patent
Estimating the term…
Abstract
Systems, methods and devices for controlled sympathectomy procedures for neuromodulation in the treatment of subjects having neoplastic conditions are disclosed. Systems, methods, and devices for interventionally treating a cancerous tumor and cancer related pain are disclosed.
Claims20
A microsurgical instrument, comprising:
- an elongate member defining a longitudinal axis, and having proximal and distal ends, the elongate member configured for passage within a lumen of a subject, the elongate member including a biasing segment configured to at least partially engage an internal wall portion defining the lumen;
- one or more electrodes configured to apply stimulation to a target neural structure within or adjacent the lumen;
- and
- one or more physiological sensors configured to emit a signal representative of physiological data of the target neural structure.
1 more element
A method, comprising:
- introducing a microsurgical tool within a lumen of a patient to a position within a vicinity of a target neural tissue, the microsurgical tool including a delivery sheath and a guide member;
- deploying the guide member from the delivery sheath whereby a distal end segment of the guide member is exposed within the lumen;
- delivering through the microsurgical tool at least one of an energy and a substance to the target neural tissue;
- monitoring with one or more physiological sensors mounted to at least one of the delivery sheath and the guide member a physiological response of the target neural tissue to the at least one of an energy and a substance;
- receiving by a controller in communication with the one or more physiological sensors signals generated by the one or more physiological sensors;
- and
- controlling, by the controller, operation of the microsurgical tool based on physiological data associated with the generated signals, including:
- determining a condition of the target neural tissue;
- and
- controlling output of the at least one of an energy and a substance based on the determined condition.
7 more elements
A method, comprising the steps of:
- introducing a microsurgical tool within a lumen of a patient;
- advancing the microsurgical tool within the lumen to a vicinity adjacent target neural tissue;
- delivering with the microsurgical tool at least one of an energy and a substance through a wall portion of the lumen and within the vicinity adjacent the target neural tissue to impart a therapeutic effect on the target neural tissue;
- and
- monitoring, with one or more sensors coupled to a distal end segment of the microsurgical tool, one or more conditions of the target neural tissue, the one or more sensors in communication with a controller.
2 more elements
Dependencies are inferred from the claim text.