Optimized solid substrates, tools for use with same and uses thereof for promoting cell and tissue growth
AssigneeCartiheal (2009) Ltd.
InventorsNir Altschuler, Amir Goren
Life of this patent
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Abstract
This invention provides optimized solid substrates for promoting cell or tissue growth or restored function, which solid substrate comprises aragonite and is characterized by a specific fluid uptake capacity value of at least 75%, or a contact angle value of less than 60 degrees when in contact with a fluid and which is further characterized by tapered sides and tools for implantation of optimized solid substrates.
Claims20
A solid substrate for treating a defect, disorder or disease, the solid substrate
- comprising a coral or coral derivative characterized by:
- a specific fluid uptake capacity value of at least 75%, by having a contact angle value of less than 60 degrees, when in contact with a fluid, or a combination thereof;
- a conical frustum shape or a pyramidal frustum shape;
- and
- a tapered side at an angle of from about 0.75 to about 4 degrees from a longitudinal axis along the solid substrate.
A method for treating a defect, disorder or disease, the method comprising implanting a solid substrate for promoting cell or tissue growth at a tissue site, wherein the solid substrate comprises a coral or coral derivative characterized by:
- a specific fluid uptake capacity value of at least 75% or is characterized by having a contact angle value of less than 60 degrees, when in contact with a fluid;
- a conical frustum shape or a pyramidal frustum shape;
- and
- a tapered side at an angle of from about 0.75 to about 4 degrees from a longitudinal axis along the solid substrate.
Dependencies are inferred from the claim text.