Method for Preparing an Intramammary Teat Sealing Composition and Sealing Composition Obtained By Such Process
AssigneeFilid Tecnologia Farmacêutica Ltda (ME)
InventorClaudio Mascaro
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Abstract
The present invention is about a method of preparation and a pharmaceutical form of an injectable intramammary teat sealing composition for use in the veterinary industry. Intramammary teat sealant composition, which includes organic glyceryl monostearate or calcium stearate, with particle size between 30 and 100 μm, in addition to mineral oil, titanium dioxide and stabilizer, in the absence of water.
Claims12
An intramammary teat sealant composition, wherein said composition is injectable and comprises organic salt of glyceryl monostearate or calcium stearate, with particle size between 30 and 100 μm, in addition to mineral oil, titanium dioxide and stabilizer, in the absence of water.
A method of preparing an intramammary teat sealing composition, comprising the following steps:
- micronizing glyceryl monostearate or salt derived from stearic acid, calcium, to a particle size between 30 and 100 μm (component a);
- dissolving the preservatives in the mineral oil while stirring;
- slowly adding, while stirring, the micronized calcium stearate (or component a);
- and then slowly adding anatase titanium dioxide under stirring;
- maintaining constant stirring between 80 and 120 rpm for 1 to 3 h;
- and
- unloading the product and filling it into syringes.
A method of preparing intramammary teat sealing composition, comprising the following steps:
- micronizing glyceryl monostearate or calcium stearate to a particle size between 30 and 60 μm;
- dissolving the preservatives in the mineral oil while stirring;
- slowly adding glyceryl monostearate or micronized calcium stearate while stirring at 50 to 200 rpm, and then adding anatase titanium dioxide slowly while still stirring;
- maintaining constant stirring between 80 and 120 rpm for 1 to 3 h;
- and
- unloading the product and filling it in 4 g syringes.
Dependencies are inferred from the claim text.