US 2024/0374882 A1 · DEVICE AND METHOD FOR PREPARING MICRONEEDLE

Abstract

A device and methods for producing microneedles includes a microneedle female mold, a vacuum chamber, a filling mechanism and an evacuation mechanism. The vacuum chamber includes a feeding cavity, a filling cavity and a discharging cavity, which are independent of one another. The feeding cavity receives the microneedle female mold therein in non-negative pressure state, and the evacuation mechanism evacuates the feeding cavity that has received the microneedle female mold therein. The filling cavity receives, in negative pressure state, the microneedle female mold transported from the feeding cavity in negative pressure state. The discharging cavity receives, in negative pressure state, the microneedle female mold transported from the filling cavity in negative pressure state and to undergo vacuum destruction after the microneedle female mold is received therein. The device and methods more efficiently produces microneedles in large batches and ensuring formation quality of the produced microneedles.

Claims26

Dependent claims

A device for producing microneedles, comprising a microneedle female mold, a vacuum chamber, a filling mechanism and an evacuation mechanism, a surface of the microneedle female mold provided with grooves matching with the microneedles, the filling mechanism at least partially disposed in the vacuum chamber and configured to release a solution for producing the microneedles, the evacuation mechanism connected to the vacuum chamber and configured to evacuate the vacuum chamber, the vacuum chamber comprising a feeding cavity, a filling cavity and a discharging cavity, which are independent of one another,

the feeding cavity configured to receive the microneedle female mold in a non-negative pressure state,
the evacuation mechanism configured to evacuate the feeding cavity that has received the microneedle female mold therein,
the filling cavity configured to receive, in a negative pressure state, the microneedle female mold transported from the feeding cavity in the negative pressure state,
the discharging cavity configured to receive, in the negative pressure state, the microneedle female mold transported from the filling cavity in the negative pressure state and to undergo vacuum destruction after the microneedle female mold is received therein.

1 more element

A method for producing microneedles, comprising:

providing a microneedle female mold, a surface of the microneedle female mold provided with grooves matching with the microneedles;
placing the microneedle female mold into a feeding cavity in a non-negative pressure state and then drawing a vacuum in the feeding cavity by an evacuation mechanism so that the feeding cavity and the microneedle female mold are both in a negative pressure state;
transporting the microneedle female mold in the negative pressure state from the feeding cavity in the negative pressure state into a filling cavity in the negative pressure state, casting a solution for producing the microneedles, in the negative pressure state, onto the surface of the microneedle female mold by a filling mechanism and performing a leveling process on the microneedle female mold with the solution cast thereon by a leveling mechanism so that the solution is uniformly flattened on the surface of the microneedle female mold;
transporting the microneedle female mold with the solution casted thereon from the filling cavity in the negative pressure state into a discharging cavity in the negative pressure state and maintaining the filling cavity in the negative pressure state;
after the microneedle female mold with the solution casted thereon is transported into the discharging cavity in the negative pressure state, destroying a vacuum in the discharging cavity in the negative pressure state so that the discharging cavity is in the non-negative pressure state, and obtaining the microneedle female mold with the solution thereon;
and
after the microneedle female mold with the solution thereon solidifies and is molded, performing a demolding process, thereby obtaining the microneedles.

4 more elements

A method for producing microneedles, comprising:

providing a microneedle female mold and a vacuum chamber, a surface of the microneedle female mold provided with grooves matching with the microneedles, the vacuum chamber comprising a filling cavity and a discharging cavity, which are independent of each other;
placing the microneedle female mold into the filling cavity in a non-negative pressure state and casting a solution for producing the microneedles onto the surface of the microneedle female mold by a filling mechanism;
performing a leveling process on the microneedle female mold by a leveling mechanism so that the solution is uniformly flattened on the surface of the microneedle female mold;
drawing a vacuum in the filling cavity by an evacuation mechanism so that the filling cavity and the microneedle female mold are both in a negative pressure state;
transporting the microneedle female mold having undergone the leveling process into the discharging cavity in the negative pressure state, destroying a vacuum in the discharging cavity in the negative pressure state so that the discharging cavity is in the non-negative pressure state, and obtaining the microneedle female mold with the solution thereon;
and
after the microneedle female mold with the solution thereon solidifies and is molded, performing a demolding process.

4 more elements

Dependencies are inferred from the claim text.

Device and method for preparing microneedle

Life of this patent

Device and method for preparing microneedle

Life of this patent

Abstract

Claims26