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US 2024/0350629 A1Published application
Genetically engineered cell-derived vaccines
AssigneeThe Regents of the University of California
InventorsYoung Jik Kwon, Jee Young Chung
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Abstract
The disclosure provides for compositions and methods comprising cell-derived vesicles induced from cells that have been genetically engineered or infected to express specific antigen(s), and uses thereof, including as a cell-free, cell-like vaccine.
Claims31
A vaccine preparation comprising extracellular blebs from a cell that has been genetically engineered to express an antigen(s),
- wherein the extracellular blebs are produced from the cell by treating the cell with a blebbing agent, and
- wherein the antigen is displayed on the surface of the extracellular blebs.
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Dependencies are inferred from the claim text.