Antibodies specifically binding to masp-3 for the treatment of various diseases and disorders
AssigneeOmeros Corporation
InventorsW. Jason Cummings, Gregory A. Demopulos, Thomas A. Dudler, Larry W. Tjoelker, Christi L. Wood, Munehisa Yabuki
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Abstract
The present invention relates to MASP-3 inhibitory antibodies and compositions comprising such antibodies for use in inhibiting the adverse effects of MASP-3 dependent complement activation.
Claims11
A method of inhibiting alternative pathway complement activation in a mammal, the method comprising administering to a mammalian subject in need thereof an amount of a composition comprising a high affinity MASP-3 inhibitory antibody or antigen-binding fragment thereof sufficient to inhibit alternative pathway complement pathway activation in the mammal.
Dependencies are inferred from the claim text.