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US 2024/0327426 A1Published application
Crystalline forms of ceftibuten
AssigneeQpex Biopharma, Inc.
InventorsScott J. Hecker, David Jonaitis
Life of this patent
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Abstract
Disclosed herein are crystalline forms of ceftibuten, methods of making such crystalline forms, and methods of using such crystalline forms. The crystalline forms of ceftibuten may be used in combination with β-lactamase inhibitors for the treatment of bacterial infections.
Claims24
A crystalline form of a compound of Formula (I):
- or a solvate thereof.
A method of preparing a crystalline form of a compound of Formula (I):
- or a solvate thereof, wherein the crystalline form exhibits an X-ray diffraction powder diffraction pattern comprising at least three characteristic peaks, wherein said characteristic peaks are selected from a group consisting of 6.3, 9.9, 10.6, 12.5, 15.2, 18.8, 20.3, 21.0, 21.3, 21.4, 26.1, 26.3, and 30.0 degrees 2θ, the method comprising drying the compound of Formula (I) under vacuum.
Dependencies are inferred from the claim text.