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AssigneeBoston Scientific Scimed, Inc.
InventorsYen-Hao Hsu, Cristian Parisi, Joseph Thomas Delaney, JR.
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In some aspects, the present disclosure pertains to radiopaque crosslinked hydrogel compositions that comprise a crosslinked reaction product of (a) a polyamino iodinated compound and (b) a reactive polymer that comprises a plurality of reactive groups that are reactive with the amino groups of the polyamino iodinated compound. In other aspects, the present disclosure pertains to systems for forming a hydrogel composition that comprise (a) a polyamino iodinated compound and (b) a reactive polymer that comprises a plurality of reactive groups that are reactive with the amino groups of the polyamino iodinated compound. In further aspects, the present disclosure pertains to methods of treatment using such systems.
A radiopaque crosslinked hydrogel composition comprising a crosslinked reaction product of (a) a polyamino iodinated compound and (b) a reactive polymer that comprises a plurality of reactive groups that are reactive with the amino groups of the polyamino iodinated compound.
A system for forming a hydrogel composition that comprises (a) a polyamino iodinated compound and (b) a reactive polymer that comprises a plurality of reactive groups that are reactive with the amino groups of the polyamino iodinated compound.
A method of treatment comprising administering to a subject a mixture that comprises a polyamino iodinated compound and a reactive multi-arm polymer that comprises a plurality of hydrophilic polymer arms having reactive end groups that are reactive with amino groups of the polyamino iodinated compound under conditions such that the polyamino iodinated compound and the reactive multi-arm polymer crosslink after administration.
Dependencies are inferred from the claim text.