Back to results
US 2024/0294927 A1Published application
Polyamine conjugate producing yeasts
AssigneeChrysea Limited
InventorsJiufu Qin, Jens Nielsen
Life of this patent
Estimating the term…
Abstract
The invention relates to production of polyamine conjugates in yeast cells that are capable of producing at least one polyamine. The yeast cells also comprise a polyamine:glutathione ligase encoding gene and at least one polyamine synthase encoding gene but lacks a polyamine oxidase encoding gene or comprises a disrupted polyamine oxidase encoding gene. The yeast cells are capable of producing various polyamine-glutathione conjugates.
Claims14
A yeast cell capable of producing glutathione-polyamine conjugates, wherein
- the yeast cell is capable of producing at least one polyamine;
- the yeast cell comprises a polyamine:glutathione ligase encoding gene;
- the yeast cell comprises at least one polyamine synthase encoding gene;
- and
- the yeast cell lacks a polyamine oxidase encoding gene or comprises a disrupted polyamine oxidase encoding gene.
2 more elements
Dependencies are inferred from the claim text.