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US 2024/0269440 A1Published application
System and methods for treating mvo
AssigneeCorFlow Therapeutics AG
InventorsRobert S. SCHWARTZ, Martin T. ROTHMAN, Jon H. HOEM
Life of this patent
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Abstract
MVO is treated by introducing injectate into blood vessels affected by MVO at precise flow rates, while blocking retrograde flow, such that the natural pumping of the heart aids in forcing the injectate into the affected microvessels. Monitoring pressure distal of an occlusion balloon is used to determine treatment effectiveness and heart health.
Claims26
A system for treating microvascular obstruction (MVO), the system comprising:
- a catheter comprising a distal region, a proximal region, and a balloon disposed at the distal region, the distal region of the catheter sized and shaped to be positioned in a blood vessel of a patient;
- at least one pressure sensor configured to generate sensor data corresponding to pressure inside the catheter and/or pressure outside the catheter distal to the balloon;
- and
- a pump assembly coupled to the proximal region of the catheter, the pump assembly comprising at least one reservoir containing injectate, the pump assembly configured to pump injectate from the at least one reservoir through the catheter at a flow rate,
- wherein the pump assembly further is configured to reduce the flow rate to zero to allow compression of the patient's microvasculature to draw the injectate into occluded blood vessels to promote mixing of the injectate with obstructing matter causing MVO.
2 more elements
A method for treating microvascular obstruction (MVO), the method comprising:
- providing a catheter comprising a distal region, a proximal region, and a balloon disposed at the distal region, the distal region of the catheter sized and shaped to be positioned in a blood vessel of a patient;
- using at least one pressure sensor configured to generate sensor data corresponding to pressure inside the catheter and/or pressure outside the catheter distal to the balloon;
- and
- activating a pump assembly coupled to the proximal region of the catheter, the pump assembly comprising at least one reservoir containing injectate, the pump assembly configured to pump injectate from the at least one reservoir through the catheter at a flow rate,
- wherein the pump assembly further is configured to reduce the flow rate to zero to allow compression of the patient's microvasculature to draw the injectate into occluded blood vessels to promote mixing of the injectate with obstructing matter causing MVO.
2 more elements
A system for treating microvascular obstruction (MVO), the system comprising:
- a catheter comprising a distal region, a proximal region, and a balloon disposed at the distal region, the distal region of the catheter sized and shaped to be positioned in a blood vessel of a patient;
- and
- a pump assembly coupled to the proximal region of the catheter, the pump assembly comprising at least one reservoir containing injectate, the pump assembly configured to pump injectate from the at least one reservoir through the catheter at a flow rate during a cycle while the balloon is inflated,
- wherein the pump assembly further is configured to reduce the flow rate to zero for a time period during the cycle to allow compression of the patient's microvasculature to draw the injectate into occluded blood vessels to promote mixing of the injectate with obstructing matter causing MVO.
1 more element
Dependencies are inferred from the claim text.