Back to results
US 2024/0266158 A1Published application
Machine Difference Corrrection Method for Mass Spectrometry Apparatus
AssigneeShimadzu Corporation
InventorsNaoki KANEKO, Tatsuki OKUBO, Tomonori OSHIKAWA, Yuko KOBAYASHI, Yoshiki TAINAKA, Kohei SUZUKI, Takashi NISHIKAZE
Life of this patent
Estimating the term…
Abstract
The present disclosure provides a method for calibrating a difference in signal intensity ratio between machines in mass spectrometry.
Claims18
A method for calibrating a difference in signal intensity ratio between machines in mass spectrometry, the method comprising the steps of:
- measuring a calibrant containing not less than two calibration substances by a mass spectrometer to obtain a signal peak of each of the calibration substances;
- determining a signal peak intensity ratio of, relative to a signal peak intensity of one calibration substance of the not less than two calibration substances, a signal peak intensity of another calibration substance;
- determining a calibration formula from the signal peak intensity ratio;
- measuring a sample containing not less than two analyte substances by the mass spectrometer to obtain a signal peak of each of the analyte substances;
- determining a signal peak intensity ratio of, relative to a signal peak intensity of one analyte substance of the not less than two analyte substances, a signal peak intensity of another analyte substance;
- and
- calibrating the signal peak intensity ratio of the analyte substances using the calibration formula.
4 more elements
A machine difference calibration system of a mass spectrometer, the system comprising:
- a measuring method preparing unit for preparing a measuring method for measuring a calibrant for calculating a calibration value in a mass spectrometer;
- a calibration value calculating unit for calculating a calibration value by analysis of mass spectrometry data obtained using the measuring method;
- and
- a sample plate display part that displays a sample plate of the mass spectrometer, wherein the sample plate display part shows sample dropping positions in the measuring method.
1 more element
16-17 (canceled)
A machine difference calibration program of a mass spectrometer, the program including allowing a computer to execute
- a measuring method preparing step in which a measuring method for measuring a calibrant for calculating a calibration value in a mass spectrometer is prepared, and
- a calibration value calculating step in which a calibration value is calculated by analysis of mass spectrometry data obtained using the measuring method,
- wherein the calibrant containing not less than two calibration substances, and
- the calibration substances include a substance labeled with a stable isotope and a substance not labeled with a stable isotope.
1 more element
Dependencies are inferred from the claim text.