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AssigneeCancer Institute and Hospital
InventorsYan WANG, Baowen YUAN, Wei HUANG, Hefen YU, Jingyao ZHANG, Yunkai YANG
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An application of feature gene TRIM22 in preparing reagent for regulating expression of breast cancer-related genes is provided. The feature gene TRIM22 disclosed in the present disclosure upregulates the expression of breast cancer-related genes SIX3, GATA6, PTX3, MMP1 and DMBT1 through overexpression, and downregulates the expression of the breast cancer-related genes SOX4, CXCL10, TNF, TP63 and CXCL16 through overexpression. Therefore, the feature gene TRIM22 provided in the present disclosure can be used as a reagent product to regulate the expression of breast cancer-related genes GATA6, SIX3, SOX4, CXCL10, PTX3, TNF, TP63, MMP1, CXCL16 and DMBT1 through overexpression.
An application of a characteristic gene TRIM22 in preparing a reagent for regulating expression of breast cancer-related genes, wherein the characteristic gene regulates the expression of breast cancer-related genes SIX3, GATA6, PTX3, MMP1, and DMBT1 through overexpression, and downregulates the expression of the breast cancer-related genes SOX4, CXCL10, TNF, TP63, and CXCL16 through overexpression.
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