Multispecific antibodies specifically binding to zika virus epitopes and uses thereof

A method of preventing and/or treating Zika virus infection in a subject, the method comprises administering to a subject in need thereof a multispecific antibody, or an antigen binding fragment thereof, specifically binding to at least two distinct Zika virus epitopes, that comprises a first heavy chain comprising CDRH1, CDRH2, and CDRH3 amino acid sequences and a first light chain comprising CDRL1, CDRL2, and CDRL3 amino acid sequences, and a second heavy chain comprising CDRH1, CDRH2, and CDRH3 amino acid sequences and a second light chain comprising CDRL1, CDRL2, and CDRL3 amino acid sequences, each according to one of:

• (a) SEQ ID NOs:
• 1-5 and 7, respectively;
• (b) SEQ ID NOs:
• 1-4 and 6-7, respectively;
• (c) SEQ ID NOs:
• 19-23 and 25, respectively;
• (d) SEQ ID NOs:
• 19-22 and 24-25, respectively;
• (e) SEQ ID NOs:
• 37-41 and 34, respectively;
• (f) SEQ ID NOs:
• 37-40 and 42-43, respectively;
• (g) SEQ ID NOs:
• 55-59 and 61, respectively;
• (h) SEQ ID NOs:
• 55-58 and 60-61, respectively;
• (i) SEQ ID NOs:
• 73-77 and 79, respectively;
• or
• (j) SEQ ID NOs:
• 73-76 and 78-79, respectively,
• wherein the first heavy chain and first light chain and the second heavy chain and second light chain are different.