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US 2024/0254093 A1Published application
GPR35 Agonist Compounds
AssigneeHeptares Therapeutics Limited
InventorsMiles Stuart CONGREVE, Nigel Alan SWAIN, Giles Albert BROWN, Benjamin WHITEHURST, Neil John FLANGAN
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Abstract
The disclosures herein relate to novel compounds of formula (1): and salts and any tautomers thereof, wherein X, R1 and R2 are defined herein, and their use in treating, preventing, ameliorating, controlling or reducing the risk of disorders associated with GPR35 receptors.
Claims33
A compound of formula (1):
- or a salt or tautomer thereof, wherein;
- X is N or CH;
- R1 is H or halo;
- R2 is H, halo, optionally substituted C1-6 alkyl, optionally substituted C3-6 cycloalkyl, optionally substituted C1-6 alkoxy, optionally substituted aryl, optionally substituted heteroaryl or optionally substituted O-aryl.
1 more element
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Dependencies are inferred from the claim text.