Synthesis of (r)(+)-2-(4-chloro-2-methyl phenoxy)propanoic acid in high enantiomeric excess

Abstract

Provided herein is a process to react optical active chloroalkyl acid alkyl ester and substituted phenols in an aromatic solvent in the presence of a catalytic quantity of a quaternary ammonium salt to yield an optically active substituted phenoxy alkyl acid.

Dependencies are inferred from the claim text.