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US 2024/0252479 A1Published application
Depot administration of iloperidone
AssigneeVanda Pharmaceuticals Inc.
InventorMihael H. Polymeropoulos
Life of this patent
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Abstract
Methods of preparing and administering an injectable depot formulation of crystalline iloperidone are disclosed herein.
Claims20
A method of preparing an injectable depot formulation of crystalline iloperidone, comprising:
- combining the crystalline iloperidone with a vehicle, wherein the crystalline iloperidone is present in the vehicle at a concentration of 166.67 mg to 200 mg of crystalline iloperidone per mL of vehicle.
A method of administering an injectable depot formulation of crystalline iloperidone suspended in a vehicle, comprising:
- using a syringe, intramuscularly injecting the depot formulation over a period of about five (5) seconds or less.
A method of preparing and administering an injectable depot formulation of crystalline iloperidone suspended in an aqueous vehicle, comprising:
- combining the crystalline iloperidone with the aqueous vehicle to form a suspension, wherein the crystalline iloperidone and the aqueous vehicle are present in the suspension at a concentration of 166.67 mg to 200 mg of crystalline iloperidone per mL of aqueous vehicle;
- and
- using a syringe, intramuscularly injecting the suspension over a period of about five (5) seconds or less.
Dependencies are inferred from the claim text.