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US 2024/0252071 A1Published application
Particle-containing membrane and particulate electrode for analyte sensors
AssigneeDexCom, Inc.
InventorsPeter C. Simpson, Robert J. Boock, Matthew Wightlin, Mark C. Shults
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Abstract
Systems and methods of use involving sensors having a particle-containing domain are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.
Claims20
A system for in vivo detection a concentration of glucose, the system comprising:
- an analyte sensor configured for implantation in a host comprising:
- a working electrode having an electroactive surface, and
- a membrane located over at least a portion of the electroactive surface, the membrane comprising an enzyme domain and a particle-containing domain located more distal to the electroactive surface than the enzyme domain, wherein the particle-containing domain is configured to react with at least one interfering species;
- and
- sensor electronics configured to generate a signal associated with the concentration of glucose in the host.
2 more elements
A method of in vivo detection a concentration of glucose, the method comprising:
- providing an analyte sensor configured for implantation into a tissue of a host, the analyte sensor comprising:
- a working electrode having an electroactive surface, and
- a membrane located over at least a portion of the electroactive surface, wherein the membrane comprises an enzyme domain and a particle-containing domain located more distal to the electroactive surface than the enzyme domain and configured to react with at least one interfering species;
- electrochemically reacting the particle-containing domain with at least one interfering species;
- and
- detecting a signal from the analyte sensor, wherein the signal is indicative of a concentration of glucose.
3 more elements
Dependencies are inferred from the claim text.