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US 2024/0245765 A1Published application
Use of Ectromelia Virus for Cancer Immunotherapy and Vaccines
AssigneesThomas Jefferson University, Poximmunomics LLC
InventorsRenhuan Xu, Luis Javier Sigal, Cory Knudson, Linjuan Tang
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Abstract
The invention provides an ectromelia virus vector for expression of heterologous sequences under the control of a viral early/late promoter, and methods of use thereof for immunotherapy, cancer treatment and treatment of infectious disease.
Claims33
A recombinant ectromelia virus (ECTV) vector comprising at least one expression unit for expression of at least one heterologous nucleic acid sequence.
A vaccine composition comprising an ECTV vector.
Dependencies are inferred from the claim text.