Anti-parasitic immunological compositions
AssigneesPrommune, Inc., Board of Regents of the University of Nebraska
InventorsPaul Davis, Samer Al-Murrani
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Abstract
Anti-parasitic compounds and uses thereof. Compounds comprising a C-terminal peptide adjuvant conjugated to an N-terminal peptide antigen via a protease-cleavable linker, said peptide adjuvant comprising a peptide analog of C5a, wherein said peptide antigen comprises an antigenic epitope of a parasitic organism, such as T. gondii. Methods of therapeutic or prophylactic treatment of a parasitic infections.
Claims20
A method for therapeutic or prophylactic treatment of a parasitic infection, said method comprising administering an anti-parasitic compound to a subject in need thereof, wherein said anti-parasitic compound comprises an N-terminal peptide antigen conjugated to a C-terminal peptide adjuvant via a protease-cleavable linker, said peptide adjuvant comprising a peptide analog of C5a, wherein said peptide antigen comprises an antigenic epitope of a parasitic organism.
Dependencies are inferred from the claim text.