Method and device for synchronous extraction and analysis of multiple trace emerging organic contaminants in hairs, and application

A method for synchronous extraction and analysis of multiple trace emerging organic contaminants in hairs, comprising the following steps:

• S1, pretreatment:
• adding a hair sample to be treated together with ultrapure water into a treatment barrel (1) in a weight ratio of 1:20-40, cutting the hair sample through a cutting quartz knife (62) in the treatment barrel (1) while washing for 0.5-1 h, subsequently discharging ultrapure water and adding ultrapure whose weight is 20-40 times of the weight of the hair sample again, cutting the hair sample through the cutting quartz knife (62) in the treatment barrel (1) while washing, until the length of the hair sample is 0.5-1 cm, subsequently discharging the ultrapure water, and then grinding the hair sample for 5-10 min through a grinding plate (11) in the treatment barrel (1) to obtain hair powders;
• S2, mixing and extraction:
• drying the hair powders obtained in step S1, placing 0.1 g of dried hair powders into a centrifuge tube, adding 1 mL of ethyl acetate and 1 mL of internal standard indicator into the centrifuge tube, standing for 12 h, and then adding 4 mL of extract solution into the centrifuge tube, wherein the extract solution is prepared from n-hexane, acetone, acetonitrile and ethyl acetate in a volume ratio of 1:1:1:1, and then starting to perform centrifugal extraction, wherein the steps for centrifugal extraction are as follows:
• vortex treatment is carried out for 4 min at the rotation speed of 2000 r·min−1, then ultrasonic treatment is carried out for 20 min at the temperature of 20° C., and finally centrifugal treatment is carried out for 15 min at the rotation speed of 4000 r·min−1, centrifugal extraction is repeated 3 times, and then the obtained supernatant is merged as a supernatant raw solution;
• S3, nitrogen blowing concentration and purification:
• performing nitrogen blowing concentration on the supernatant raw solution obtained in step S2 to 1 mL, subsequently adding 20 mg of Na2SO4 powders and 100 mg of C18 powders serving as purifying fillers, then performing vortex treatment for 7 min at the rotation speed of 1200 r·min−1, then performing centrifugal treatment for 15 min at the rotation speed of 3500 r·min−1 to obtain a concentrated solution, and then transferring the concentrated solution to a glass tube;
• and
• S4, low-temperature separation:
• blowing the concentrated solution obtained in step S3 with nitrogen for 1-2 h, then adding 200 μL of methanol solution with a mass fraction of ≥99.8% for redissolving, standing for 4-6 h at the temperature of −20° C., freezing and removing a precipitate to obtain the hair raw solution after low-temperature separation and performing Liquid chromatography-tandem mass spectrometry/mass spectrometry (LC-MS/MS) and Gas chromatography-tandem mass spectrometry/mass spectrometry (GC-MS/MS) detection analysis on the hair raw solution.