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US 2024/0201173 A1Published application
Enamel Repair Visualization and Quantification
AssigneeColgate-Palmolive Company
InventorsQichao RUAN, Stacey Lavender
Life of this patent
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Abstract
The present invention relates to methods for visualizing and quantifying the repair of tooth enamel, for example, for the evaluation of dentifrice compositions for the treatment or prevention of dental caries, early erosive damage, and enamel demineralization, and the promotion of enamel repair and remineralization.
Claims13
A method for analyzing, visualizing, and/or quantifying, the repair of damaged tooth enamel resulting from the treatment of the damaged tooth enamel with a test composition, wherein the method comprises the steps of:
- (a) providing a sample of human or animal tooth or enamel have a flat or substantially flat upper surface of enamel;
- (b) covering a portion of the sample surface with an impermeable, removable coating (e.g., half of the sample surface), e.g., as a negative control;
- (c) treating the uncoated portion of the sample surface with an agent to cause damage to the enamel of the uncoated sample surface;
- (d) covering a portion of the damaged sample surface with an impermeable removable coating (e.g., half of the damaged sample surface), e.g., as a positive control;
- (e) treating the remaining portion of uncoated, damaged sample surface with the test composition, e.g., as the test surface;
- (f) removing the impermeable, removable coatings;
- and
- (g) analyzing and comparing the differences between the three portions of the sample surface (the undamaged untreated negative control surface, the damaged untreated positive control surface, and the damaged treated test surface).
5 more elements
Dependencies are inferred from the claim text.