Cell culture device with a mechanical stimulation function

A cell culture device with a function for the mechanical stimulation of biological tissues (T), comprising:

• a fluidic component wherein a well is made which is dug in a “main” direction (X),
• a first elastically deformable porous membrane, referred to as a culture membrane, integrated into said component and extending transversely to said main direction (X) to close off said well, said culture membrane comprising an upper face intended to receive a cell culture and an opposite lower face,
• a first fluidic circuit integrated into said component, comprising a first cavity made in said well under said culture membrane and intended to receive a culture medium suitable for infusing said biological tissues (T),
• a second elastically deformable non-porous membrane, referred to as the actuating membrane, integrated into said component,
• means for actuating said actuating membrane,
• wherein:
• the actuating membrane is arranged to tightly seal the bottom of said first cavity, and configured to deform under the action of said actuating means to a position wherein said actuating membrane mechanically pushes said culture membrane to deform it.