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US 2024/0200008 A1Published application
Device for manufacturing cell-derived vesicles and manufacturing method using same
AssigneeMdimune Inc.
InventorsJik Han JUNG, Byoung Jin KIM, Shin Gyu BAE
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Abstract
The present invention relates to a method for manufacturing cell-derived vesicles using a depth filter. The present invention has the effect of enabling cell-derived vesicles to be manufactured stably, economically, and in large quantities through a simplified process.
Claims20
A method for manufacturing cell-derived vesicles using a depth filter, comprising:
- a) extruding cells through a depth filter;
- and
- b) obtaining cell-derived vesicles from the extruded solution.
A method for manufacturing cell-derived vesicles with reduced risk of exposure to external contamination comprising:
- a) harvesting cells by passing a cell culture solution containing the cells through a depth filter;
- b) resuspending the harvested cells by supplying a cell suspension;
- c) extruding the cells resuspended in step b) through a depth filter;
- and
- d) obtaining cell-derived vesicles from the extruded solution,
- wherein steps a) to d) are performed in one device.
3 more elements
Dependencies are inferred from the claim text.