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US 2024/0199710 A1Published application
Bioactive polypeptides and methods related thereto
AssigneeEcolibrium Biologicals Holdings Limited
InventorsStephen Reynold FORD, Mildred Marsha ORMSKIRK, Travis GLARE
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Abstract
The invention relates to bioactive polypeptides from strains of Brevibacillus laterosporus which have useful activity including pesticidal activity such as insecticidal activity, compositions comprising said polypeptides, and methods for using the polypeptides and compositions, for example in methods of controlling agriculturally-important pests including insect pests.
Claims21
An isolated, purified, recombinant or synthetic polypeptide selected from the group comprising:
- a) a polypeptide comprising or consisting of the amino acid sequence depicted in any one of Sequence ID No.s 1 to 87;
- b) a polypeptide comprising or consisting of the amino acid sequence corresponding to residues 89 to 322 of Sequence ID No. 1;
- c) a polypeptide comprising or consisting of the amino acid sequence corresponding to residues 91 to 322 of Sequence ID No. 1;
- d) a polypeptide comprising or consisting of the amino acid sequence corresponding to residues 147 to 322 of Sequence ID No. 1;
- e) a polypeptide comprising or consisting of the amino acid sequence corresponding to residues 74 to 307 of Sequence ID No. 32;
- f) a polypeptide comprising or consisting of the amino acid sequence corresponding to residues 76 to 307 of Sequence ID No. 32;
- g) a polypeptide comprising or consisting of the amino acid sequence corresponding to residues 132 to 307 of Sequence ID No. 32;
- h) a polypeptide comprising or consisting of the amino acid sequence corresponding to residues 89 to 322 of Sequence ID No. 58;
- i) a polypeptide comprising or consisting of the amino acid sequence corresponding to residues 91 to 322 of Sequence ID No. 58;
- j) a polypeptide comprising or consisting of the amino acid sequence corresponding to residues 147 to 322 of Sequence ID No. 58;
- k) a polypeptide comprising or consisting of at least 10 contiguous amino acids from any one of a) to j) above;
- l) a polypeptide comprising or consisting of at least 20 contiguous amino acids from any one of a) to j) above;
- m) a polypeptide comprising or consisting of at least about 10 contiguous amino acids from any one of a) to l) above, wherein said polypeptide has glycoside hydrolase activity;
- n) a polypeptide comprising or consisting of at least about 10 contiguous amino acids from any one of a) to m) above, wherein said polypeptide has chitinase activity or one or more chitinase domains;
- o) a polypeptide having at least about 90% amino acid identity to any one of a) to n) above;
- p) a polypeptide having at least about 95% amino acid identity to any one of a) to n) above;
- q) any combination of any two or more of a) to p) above.
14 more elements
Dependencies are inferred from the claim text.