NOVEL N-ACYL-[3-SUBSTITUTED]-[8-SUBSTITUTED]-5,6-DIHYDRO-[1,2,4]TRIAZOLO[4,3-a]PYRAZINES AS SELECTIVE NK-3 RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITION, METHODS FOR USE IN NK-3 RECEPTOR-MEDIATED DISORDERS
AssigneeOgeda SA
InventorsHamid Hoveyda, Guillaume Dutheuil, Graeme Fraser
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Abstract
A method for treating and/or preventing polycystic ovary syndrome (PCOS) including the administration, to a patient in need thereof, of a pharmaceutically effective amount of a compound of Formula I or a pharmaceutically acceptable solvate thereof.
Claims8
A method of preventing and/or treating moderate and severe hot flashes in a patient, comprising administering to a patient in need thereof for at least four weeks a pharmaceutically effective amount of the following compound:
- wherein the frequency of hot flashes in the patient after at least four weeks of treatment is reduced compared to the frequency of hot flashes in the patient before at least four weeks of treatment.
A method for preventing and/or treating moderate and severe hot flashes in a patient, comprising administering to a patient in need thereof for at least four weeks a pharmaceutically effective amount of the following compound:
- wherein the severity of hot flashes in the patient after at least four weeks of treatment is reduced compared to the severity of hot flashes in the patient before at least four weeks of treatment.
Dependencies are inferred from the claim text.