Quinone compound and pharmaceutical use thereof
AssigneeNanjing Shupeng Life Science Co., Ltd.
InventorsChuanjun WEN, Junyi ZOU, Fenyong SUN
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Abstract
The present invention discloses a quinone compound and pharmaceutical use thereof. The quinone compound has a chemical structure of a general formula (I). The quinone compound has a phamaceutical value and a unique analgesic effect, inhibits inflammation and inhibits invasion and growth of tumor cells. The quinone compound can be used for preparing analgesic drugs, anti-tumor drugs, anti-inflammatory drugs, drugs for treating autoimmune diseases and the like.
Claims12
A compound of a formula (I) or a pharmaceutically acceptable salt, ester, stereoisomer, solvent compound or prodrug thereof,
- wherein
- R1 is selected from —OH, —OR, —OC(O)R, —NH2, —NHR, —SH or —SR;
- R2 is selected from H, C1-C3 alkyl, NH2, NHR or —COOH;
- R3 is selected from H, C1-C3 alkyl, OH, NH2, NHR, —COOH or SH;
- R4 is selected from H, C1-C3 alkyl or C6-C10 aryl;
- R5 is selected from H, C1-C3 alkyl, OH, NH2, NHR, —COOH or SH;
- R6 is selected from H, C1-C3 alkyl, OH, NH2, NHR, —COOH or SH;
- R is C1-C6 alkyl;
- and preferably, the R is C1-C3 alkyl.
Compounds or pharmaceutically acceptable salts, esters, stereoisomers, solvent compounds or prodrugs thereof shown as follows:
A method for preparing the compound of a formula (II):
Dependencies are inferred from the claim text.