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AssigneeK.D. Pharma Bexbach GmbH
InventorsGideon GIESSELMANN, Roberto FRONZONI, Elia RAMOS-TERCERO, Denitsa SHOPOVA-GOSPODINOVA
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A method and apparatus for isolating a first substance from a mixture by chromatography, the mixture including at least a second substance which in the chromatography is subject to a greater retention than the first substance, and having a third substance which in the chromatography is subject to a lower retention than the first substance. The mixture is supplied to a chromatography apparatus having multiple interconnected chromatography columns. The apparatus is supplied with the mixture and an eluent, and the second substance is withdrawn as an extract and the first substance as a raffinate. The third substance is withdrawn as an extract. Usefully the third substance and the second substance are withdrawn jointly as an extract.
1-19. (canceled)
A method for separating a first substance from a substance mixture by chromatography, wherein the substance mixture comprises the first substance, at least one second substance and at least one third substance, the method comprising the steps of:
An apparatus for separating a first substance from a substance mixture by chromatography, comprising:
A computer program product that is loadable directly into an internal memory of a digital computer, the computer program product comprising software sections that, when the computer program product is running on a computer, carry out steps of a method for controlling and/or regulating a substance separation apparatus, wherein the substance separation apparatus comprises a plurality of interconnected chromatography columns and is provided for separating a first substance from a substance mixture, wherein the substance mixture comprises at least one second substance that is subject to a longer retention than the first substance when chromatography is carried out, and comprises a third substance that is subject to a shorter retention than the first substance during chromatography, the substance mixture and an eluent being fed to the apparatus, and the second substance being withdrawn as an extract and the first substance being withdrawn as a raffinate, wherein substance flows of the substance mixture, of the eluent, of the raffinate and/or of the extract in the apparatus are adjusted so that the third substance is withdrawn as an extract.
Dependencies are inferred from the claim text.