Processes and devices for delivery of fluid by chemical reaction

A device for delivering a therapeutic fluid by chemical reaction, the device comprising:

• a barrel having a first chamber, a second chamber, and a third chamber;
• a piston positioned between the first and second chambers of the barrel;
• a spring configured to move the piston;
• a plunger positioned between the second and third chambers of the barrel;
• and
• an actuator configured to rotate relative to the barrel between a first configuration and a second configuration;
• wherein:
• in the first configuration, the first chamber contains a first reagent, the second chamber contains a second reagent and is separated from the first chamber by the piston, the piston forming a sealing interface between the first and second chambers, and the third chamber contains the therapeutic fluid;
• and
• in the second configuration, the spring moves the piston to place the first chamber in communication with the second chamber such that the first and second reagents react to generate a gas that drives the plunger to deliver the therapeutic fluid from the third chamber.

A device for delivering a therapeutic fluid by chemical reaction, the device having a loaded configuration and a delivery configuration, the device comprising:

• a barrel;
• an actuator that moves in a first longitudinal direction relative to the barrel from the loaded configuration to the delivery configuration;
• a piston that moves in a second longitudinal direction opposite the first longitudinal direction of the actuator from the loaded configuration to the delivery configuration;
• and
• an anti-back drive (ABD) ring that prevents movement of the actuator in the second longitudinal direction from the delivery configuration.