A method of obtaining a three-dimensional polymer and β-tricalcium phosphate (β-TCP) scaffold structure (tissue scaffold) that allows/supports cell infiltration using an additive manufacturing process, coating with physiological buffered HA solution with deep coting method, and obtaining a biological tissue implant that allows an use of titanium mesh plate or contoured structures to increase a transmission rate of growth factors and expand the areas, wherein
- filament layers, which are connected to each other at angles that will support extracellular matrix (ECM) interaction and overlapped by connecting at 90 degrees with each other,
- overlapping the third filament layer as oblig,
- supporting vascularized tissue formation of the obtained structures together with osteoconductive effect in 50-70 micron pore structure,
- increasing a deep encapsulation of hyaluronic acid into the body by creating micro cracks on the body with the cryo-shock method or vacuum drying system of the three-dimensional tissue scaffold formed as a result of extrusion, and
- attachment and coating of the empass or hot polymer to a surface of the titanium mesh by extrusion.