Devices and methods for endoscopic plurality strip delivery

A method of treating a subject, the method comprising:

• introducing a distal portion of a medical device into a gastrointestinal tract of the subject, wherein the distal portion of the device defines a lumen that houses a shaft and a chamber proximate a distal end of the device, wherein the chamber houses a plurality of strips comprising a biocompatible material;
• positioning the distal portion of the device proximate a target site of a tissue wall that includes a defect;
• advancing the shaft distally to push the plurality of strips out of a distal opening of the device and onto the target site;
• and
• applying a biocompatible liquid, a therapeutic agent, or a balloon to the target site after applying the plurality of strips.

A method of treating a subject, the method comprising:

• introducing a distal portion of a medical device into a gastrointestinal tract of the subject, wherein the distal portion of the device includes a chamber that houses a plurality of strips comprising chitosan or derivative thereof;
• positioning the distal portion of the device proximate a target site of a tissue wall of the gastrointestinal tract that includes defect;
• and
• applying the plurality of strips to the target site by pushing the plurality of strips out of a distal opening of the device;
• wherein each strip of the plurality of strips has a variable thickness along a length of the strip, and the plurality of strips change from a planar configuration when housed within the device to a curled configuration when applied to the target site.