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US 2024/0197865 A1Published application
Compositions and methods for preventing rsv and piv3 infections
OwnerSylvia Van Den Hurk, Volker Gerdts +2inventors
InventorsSylvia Van Den Hurk, Volker Gerdts, Robert Brownlie, Ravendra Garg
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Abstract
The present invention provides immunogenic chimeric respiratory syncytial virus (RSV)-parainfluenza virus type 3 (PIV3) compounds and associated compositions, along with methods of treating, preventing and/or diagnosing RSV- and PIV3-related disorders.
Claims17
An immunogenic fusion protein comprising a polypeptide with at least 90% sequence identity to a polypeptide selected from the group consisting of:
- a polypeptide comprising amino acid residues 26 to 979 of SEQ ID NO:
- 1,
- a polypeptide comprising amino acid residues 26 to 979 of SEQ ID NO:
- 3, and
- a polypeptide comprising amino acid residues 26 to 979 of SEQ ID NO:
- 5.
3 more elements
An immunogenic composition comprising:
- a polypeptide with at least 90% sequence identity to a fusion polypeptide selected from the group consisting of:
- a polypeptide comprising amino acid residues 26 to 979 of SEQ ID NO:
- 1,
- a polypeptide comprising amino acid residues 26 to 979 of SEQ ID NO:
- 3, and
- a polypeptide comprising amino acid residues 26 to 979 of SEQ ID NO:
- 5,
- and a pharmaceutically acceptable excipient.
5 more elements
Dependencies are inferred from the claim text.