Immunogenic composition and uses thereof

Abstract

Disclosed herein is an immunogenic composition for enhancing immunogenicity and treatment efficacy. The immunogenic composition comprises a nanoparticle (e.g., a nanodiamond) and an immunogenic conjugate having formula (I): X-L-Y, wherein X is an agonist module, L is a linker unit, and Y is an antigen. In the immunogenic composition, the immunogenic conjugate is coupled to the outer surface of the nanoparticle. Also encompasses herein is a method of preventing or treating a disease in a subject in need thereof, comprising administering an effective amount of the immunogenic composition set forth above to the subject.

Dependencies are inferred from the claim text.