Use of extensively hydrolysed protein
AssigneesMJN U.S. Holdings LLC, The General Hospital Corporation
InventorsAlessio FASANO, Gabriele GROSS, Sarmauli Irianti MANURUNG, Stefania SENGER, Eric Alexander Franciscus VAN TOL
Life of this patent
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Abstract
The present application relates to extensively hydrolysed protein, and compositions comprising extensively hydrolysed protein, for use in reducing the risk of intestinal inflammation, reducing the risk of intestinal tissue damage, and/or improving gut barrier function, in an infant.
Claims50
Extensively hydrolysed casein for use in reducing the risk of intestinal inflammation, intestinal tissue damage, or both, in a preterm infant.
Extensively hydrolysed casein for use in improving gut barrier function in a preterm infant.
Extensively hydrolysed casein for use in downregulating expression of IL-1β, IL-8, TNFR2, or any combination thereof, in a preterm infant.
A composition for use in:
- reducing the risk of intestinal inflammation, intestinal tissue damage, or both;
- improving gut barrier function;
- and/or, downregulating expression of IL-1β, IL-8, TNFR2, or any combination thereof, in a preterm infant, wherein the composition comprises extensively hydrolysed casein.
A method for reducing the risk of intestinal inflammation, intestinal tissue damage, or both, in a preterm infant, the method comprising the step of administering extensively hydrolysed casein to the preterm infant.
A method for improving gut barrier function in a preterm infant the method comprising the step of administering extensively hydrolysed casein to the preterm infant.
A method for downregulating expression of IL-1β, IL-8, TNFR2, or any combination thereof, in a preterm infant, the method comprising the step of administering extensively hydrolysed casein to the preterm infant.
A method for:
- reducing the risk of intestinal inflammation, intestinal tissue damage, or both;
- improving gut barrier function;
- and/or, downregulating expression of IL-1β, IL-8, TNFR2, or any combination thereof, in a preterm infant, the method comprising administering a composition comprising extensively hydrolysed casein to the preterm infant.
Dependencies are inferred from the claim text.