Pharmaceutical composition and use thereof

A pharmaceutical composition, wherein the pharmaceutical composition is an injectable or infusable pharmaceutical composition, the pharmaceutical composition comprising:

• a) a pharmaceutically acceptable solvent,
• b) a first compound comprising diclofenac and lornoxicam, or a pharmaceutically acceptable salt or solvate thereof,
• c) a second compound comprising metamizole or tramadol or a pharmaceutically acceptable salt or solvate thereof, and
• d) a third compound selected as at least one benzodiazepine or a pharmaceutically acceptable salt or solvate thereof,
• the pharmaceutical composition further comprising a cortisone derivative or a pharmaceutically acceptable salt or solvate thereof.

A pharmaceutical composition for use in the preemptive or palliative treatment of pain in a mammal, preferably in an human, wherein preferably pain is selected from the group consisting of chronic pain, inflammatory pain, neuropathic pain, acute pain, surgical pain, cancer-related pain, disc prolapse-related pain, low-back pain, neck ache, back pain, rheumatic pain, tension-type pain, tension-type headache, migraine pain, radicular pain, tooth pain, joint pain, and pain of the locomotor apparatus, wherein the pharmaceutical composition is administered to the mammal, preferably human, until a visual analog scale (VAS) rating of pain of 3 or less is reached, and

• wherein the pharmaceutical composition is an injectable or infusable pharmaceutical composition, the pharmaceutical composition comprising:
• a) a pharmaceutically acceptable solvent,
• b) a first compound comprising diclofenac or a pharmaceutically acceptable salt or solvate thereof,
• c) a second compound comprising metamizole or tramadol or a pharmaceutically acceptable salt or solvate thereof, and
• d) a third compound selected as at least one benzodiazepine or a pharmaceutically acceptable salt or solvate thereof.