Expandable structured dosage form for prolonged drug delivery

A pharmaceutical dosage form comprising:

• a drug-containing solid having an outer surface and an internal three dimensional structural framework comprising a plurality of criss-crossed stacked layers of fibrous structural elements with average fiber thickness in the range of 5 μm to 2.5 mm, said framework contiguous with and terminating at said outer surface;
• said fibrous structural elements comprising at least an active pharmaceutical ingredient, at least an absorptive excipient having a molecular weight greater than 50 kg/mol and being mutually soluble with a physiological fluid, and at least a hydrophilic surface composition;
• said fibrous structural elements further having segments spaced apart from like segments of adjoining fibrous elements, thereby defining free spaces, wherein a plurality of adjacent free spaces of successive layers combine to define one or more interconnected free spaces forming an open pore network;
• whereby
• upon immersion in a physiological fluid said open pore network enables uniform wetting of the structural framework, and the drug-containing solid transitions to a viscous mass, thereby expanding in all dimensions.