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US 2024/0197635 A1Published application
Dissociating polymer matrix compositions of fulvestrant and methods of their making and use
AssigneeVeraMorph LLC
InventorPaul Douglas Godfrin
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Abstract
The present disclosure relates to the composition and methods of manufacturing and use of dissociating polymeric matrix oral dosages (disintegrating pre-formed oral dosage hydrogels) loaded with fulvestrant as an orally delivered therapy for the treatment of diseases, particularly cancer and especially metastatic breast cancer.
Claims28
A composition comprising:
- a dissociating polymer matrix comprising single- or multi-component polymer chains connected by one or more hydrolytically degradable cross-linkers covalently linked to said polymer chains defining pores within the polymer matrix and
- fulvestrant encapsulated within the pores of the dissociating polymer matrix.
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Dependencies are inferred from the claim text.