Apparatus and method for nerve ablation in the wall of the gastointestinal tract

An ablation device comprising:

• a catheter comprising
• an expandable member configured to stretch a wall of a gastro-intestinal (GI) lumen and to generate a fixed distance between a center of the catheter and the wall;
• a laser transmitting element configured to couple to the catheter and to transmit a first laser beam and a second laser beam;
• wherein the first laser beam has a first infrared wavelength and a first spot diameter and is configured to cause ablative damage in a region of the wall as a result of its impingement thereon;
• and wherein the second laser beam has a second blue-red wavelength and a second spot diameter, and is configured to be transmitted to a second region of the wall to enable detection of modifications in the region of the wall resulting from the impingement of the first laser beam thereon;
• and
• a rotatable deflective optical element functionally coupled with a laser emitting element and configured to direct the first and/or second laser beam to a region on and/or beneath the wall;
• wherein the first and second laser beams are configured to be transmitted towards and/or cause ablative damage to different regions of the wall.