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US 2024/0197295 A1Published application
System and method for immune and molecular biosensing via toothbrush
AssigneeImmune Labs LLC
InventorsMarcelo Freire, Adir Abergel
Life of this patent
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Abstract
A toothbrush biometric monitoring system includes a multimodal sensing diagnostic system integrally incorporated into an oral hygiene device. The multimodal sensing diagnostic system is configured to capture a target molecule, detect molecular cues, and generate a signal in response to binding of a binding moiety and one or more biomarkers.
Claims20
A biometric oral monitoring system comprising:
- an oral hygiene device including a display;
- a multimodal sensing diagnostic system integrally incorporated into the oral hygiene device and configured to capture and evaluate at least one biomarker relative to normal and abnormal levels in a human, the multimodal sensing diagnostic system including:
- an absorbing layer configured to capture analytes of a biological oral fluid,
- a multimodal sensing layer configured to detect molecular cues,
- a recognition moiety configured to bind to one or more analytes, wherein the binding moiety interacts with at least one biomarker present in the biological fluid to detect the at least one biomarker,
- an electrically conductive surface electrically coupled to the recognition moiety and configured to generate a signal in response to binding of the binding moiety and the at least one biomarker, wherein the signal is indicative of a parameter value of the at least one biomarker, and
- a logic circuit communicatively coupled to the electrically conductive surface and the display, wherein the logic circuit is configured to receive the signal from the electrically conductive surface and display an indication on the display based on the signal.
4 more elements
A device comprising:
- an electrically conductive layer having attached thereto one or more binding moieties configured to bind one or more biomarkers of a biological oral fluid, wherein binding of the one or more biomarkers to the binding moieties causes a change in one or more electrical characteristics of the conductive layer;
- one or more base layers positioned in contact with the electrically conductive layer, wherein the one or more base layers comprise at least one of ceramic, silica, polymer, or plastic;
- and
- a logic circuit coupled to an antenna, the logic circuit coupled to the electrically conductive layer, wherein the logic circuit is configured to, in response to the change in one or more electrical characteristics of the electrically conductive layer caused by the binding of the one or more biomarkers, transmit a signal, via the antenna, to an external device, and wherein the signal is indicative of the change.
1 more element
A method for detecting a condition or disorders associated with oral and systemic health in a subject, the method comprising:
- detecting altered level of at least one biomarker related to monitoring of homeostasis of diagnostic infectious diseases and immunological changes by detecting binding of the one or more biomarkers to one or more binding moieties that causes a change in at least one electrical characteristic of an electrically conductive layer, and
- in response the change in the at least one electrical characteristic caused by the binding of the one or more biomarkers to the one or more binding moieties, transmitting a signal indicating the change.
Dependencies are inferred from the claim text.