Medication adherence and/or counterfeit detection wearable electronic device

A system to determine medication adherence, the system comprising:

• a chemical marker sensor configured to detect one or more markers of a therapeutic agent in sweat vapor of a user;
• a verification sensor configured to detect whether the system is less than a threshold distance from skin;
• an electrocardiogramansor configured to detect a manifestation of an expected effect of the therapeutic agent on the user;
• and
• a processor communicatively coupled to the chemical marker sensor, the verification sensor, and the heart-beat sensor, and configured to calculate a confidence level indicative of whether the user has taken the therapeutic agent based on the chemical marker sensor detecting the one or more markers in the sweat vapor, the verification sensor detecting that the system is less than the threshold distance from skin, and the ECG sensor detecting the manifestation of the expected effect of the therapeutic agent on the user.

A system to determine medication adherence, the system comprising:

• a chemical marker sensor configured to detect one or more markers of a therapeutic agent in sweat vapor of a user;
• a verification sensor configured to detect whether the system is less than a threshold distance from skin;
• a photoplethysmograph (PPG) sensor configured to detect a manifestation of an expected effect of the therapeutic agent on the user;
• and
• a processor communicatively coupled to the chemical marker sensor, the verification sensor, and the PPG sensor and configured to calculate a confidence level indicative of whether the user has taken the therapeutic agent based on the chemical marker sensor detecting the one or more markers in the sweat vapor, the verification sensor detecting that the system is less than the threshold distance from skin, and the PPG sensor detecting the manifestation of the expected effect of the therapeutic agent on the user.

A system to determine medication adherence, the system comprising:

• a chemical marker sensor configured to detect one or more markers of a therapeutic agent in sweat vapor of a user;
• a verification sensor configured to detect whether the system is less than a threshold distance from skin;
• an accelerometer configured to detect a manifestation of an expected effect of the therapeutic agent on the user;
• and
• a processor communicatively coupled to the chemical marker sensor, the verification sensor, and the accelerometer and configured to calculate a confidence level indicative of whether the user has taken the therapeutic agent based on the chemical marker sensor detecting the one or more markers in the sweat vapor, the verification sensor detecting that the system is less than the threshold distance from skin, and the accelerometer detecting the manifestation of the expected effect of the therapeutic agent on the user.

A system to determine medication adherence, the system comprising:

• a chemical marker sensor configured to detect one or more markers of a therapeutic agent in sweat vapor of a user;
• a verification sensor configured to detect whether the system is less than a threshold distance from skin;
• a microphone or audio sensor configured to detect a manifestation of an expected effect of the therapeutic agent on the user;
• and
• a processor communicatively coupled to the chemical marker sensor, the verification sensor, and the microphone or audio sensor and configured to calculate a confidence level indicative of whether the user has taken the therapeutic agent based on the chemical marker sensor detecting the one or more markers in the sweat vapor, the verification sensor detecting that the system is less than the threshold distance from skin, and the microphone or audio sensor detecting the manifestation of the expected effect of the therapeutic agent on the user.

A system to determine medication adherence, the system comprising:

• a chemical marker sensor configured to detect one or more markers of a therapeutic agent in sweat vapor of a user;
• a verification sensor configured to detect whether the system is less than a threshold distance from skin;
• a third sensor configured to detect a change in a movement pattern or motion pattern of the user indicative of a manifestation of an expected effect of the therapeutic agent on the user;
• and
• a processor communicatively coupled to the chemical marker sensor, the verification sensor, and the third sensor, and configured to calculate a confidence level indicative of whether the user has taken the therapeutic agent based on the chemical marker sensor detecting the one or more markers in the sweat vapor, the verification sensor detecting that the system is less than the threshold distance from skin, and the third sensor detecting the change in the movement pattern or motion pattern of the user indicative of the manifestation of the expected effect of the therapeutic agent on the user.