US 2024/0197211 A1 · SYSTEM AND METHOD FOR BLOOD GLUCOSE MONITORING BASED ON HEART RATE VARIABILITY

Abstract

The concept of this invention is a method to calculate the glucose management index based on calculated instantaneous plasma blood glucose levels from heart rate variability (HRV) parameters received by a QRS detector and ECG sensor. The invented method starts with the extraction of clean electrocardiogram intervals, and then calculates an aggregation of HRV collections satisfying the coverage factor to reveal the ability to control the glucose and quantitative glucose level from long-term HRV; and ambulatory glucose profile along with other statistical glycemic measures by calculating plasma glucose levels from selected short term HRV. The patient, caregiver and doctor can access this glucose profile remotely by a smartphone or cloudbased processing and monitoring system, which can send out an emotionally intelligent message to the user without generating stress, but instead of giving gentle advice and tips for current glycemic state helping to undertake appropriate therapeutic measures.

Claims18

Dependent claims

A system for non-invasive monitoring glucose level comprising a device for ECG sensing and a personal device, wherein the personal device is configured to

receive ECG samples from the device for ECG sensing;
perform beat detection, beat classification, and annotation sharing;
extract a clean ECG signal;
calculate an extended set of HRV parameters;
calculate an aggregation of HRV collections with predefined window sizes and offsets;
apply a set of threshold decisions to detect ability to regulate a predefined glucose level;
calculate an equivalent to HbA1C and plasma glucose levels;
form reports containing AGP and achieved glucose statistics.

5 more elements

A method of detecting the glucose level by non-invasive method comprising:

analyzing ECG annotations;
extracting a clean ECG interval;
calculating an extended set of HRV parameters;
calculating an aggregation of HRV collections with predefined window sizes and offsets;
applying a set of threshold decisions to detect ability to regulate a predefined glucose level;
calculating an equivalent to HbA1C and plasma glucose levels;
forming reports containing AGP and achieved glucose statistics.

4 more elements

Dependencies are inferred from the claim text.

System and method for blood glucose monitoring based on heart rate variability

Life of this patent

System and method for blood glucose monitoring based on heart rate variability

Life of this patent

Abstract

Claims18