Method of and system for obesity treatment using laparoscopically-guided 3d-stereoscopic and ir-thermographic intra-abdominal visceral fat aspiration, supported by real-time cytokine sensing and profiling and augmented-reality (ar) display and visual sample tagging

A 3D-stereoscopic IR-thermographic laparoscopic visceral fat removal system comprising:

• a 3D stereoscopic laparoscopic camera system having a pair of digital cameras supporting left and right fields of view for generating stereoscopic image pairs, and one or more IR image sensors mounted along at least one of said left and right fields of view to generate an IR thermographic image;
• a 3D stereoscopic display system selectively displaying 3D stereoscopic images of the patient's mesentery region, and IR thermographic images of the patient's mesentery region with or without color mapping of pixels in said IR thermographic images;
• and
• a powered tissue aspiration instrument in communication with a fat tissue vacuum source and collection tank, for selectively aspirating visceral fat tissue from a patient's mesentery region while viewing 3D stereoscopic images of the patient's mesentery region, and/or IR thermographic images of the patient's mesentery region.

A cytokine detection and analysis chip comprising:

• (i) a micro-fluidic detection chip module, wherein each sensing channel has an input micro-fluidic inflow gate operably connected to the powered aspiration instrument inserted and guided within the patient, and also connected to a micro-fluidic flow detection channel that is connected to an output microfluidic outflow gate, that is operably connected to a flow channel vacuum source;
• (ii) a flow channel flushing agent module in fluid communication with each micro-fluidic flow detection channel, for flushing the channel with an appropriate flushing agent under the control of the system controller;
• (iii) a flow channel liquid cytokine binding agent module in fluid communication with each micro-fluidic flow detection channel, for supplying the channel with an appropriate cytokine binding agent under the control of the system controller, suited for the particular cytokine to be detected within this specific flow channel on the chip;
• (iv) an ultrasonic-based electrode cleaning module in fluid communication with each micro-fluidic flow detection channel, for ultrasonically cleaning the channel with ultrasonic energy and applied fluid under the control of the system controller;
• (v) a flow channel impedance measuring module in fluid communication with each micro-fluidic flow detection channel, for electrically measuring the impedance (Z) characteristics of the fat sample flowing within the sensing channel under the control of the system controller,
• (vi) an impedance data processing module in communication with the flow channel impedance measuring circuit module, for processing the electrical data collected by the impedance measuring circuit under the control of the system controller;
• (vii) a cytokine detection module in communication with the impedance data processor for processing the data and detecting the type and quantity (i.e. concentration) of cytokine molecules in the specific flow sensing channel aboard the chip device, for providing digital output to the AR display controller while it is receiving captured digital image frames and indices during the time of fat sampling, and compositing the data input to generate a composite video output for visual display on the 3D stereoscopic IR display system.