Methods and devices for directing dissipation of a charged active agent after administration

18) A method for directing dissipation of a charged active agent, the method comprising:

• a) placing two electrodes against a subject's skin, the two electrodes configured to receive opposing charges to generate a directional electric field between the two electrodes and approximately parallel to the skin;
• b) subcutaneously or intramuscularly administering the charged active agent between the two electrodes, the charged active agent comprising a net negative or net positive charge at physiological pH;
• and
• c) applying a positive charge to one of the two electrodes and a negative charge to another of the two electrodes to produce the directional electric field, thereby electrically directing dissipation of the administered charged active agent towards one of the two electrodes and away from another of the two electrodes.

20) A method for directing dissipation of a charged active agent, the method comprising:

• a) subcutaneously or intramuscularly administering a charged active agent into a subject, the charged active agent comprising a net negative or net positive charge at physiological pH;
• b) placing two electrodes against the subject's skin, the two electrodes configured to receive opposing charges to generate a directional electric field approximately parallel to the skin and at the administered charged active agent;
• and
• c) applying a positive charge to one of the two electrodes and a negative charge to another of the two electrodes to produce the directional electric field, thereby electrically directing dissipation of the administered charged active agent towards one of the two electrodes and away from the oppositely charged electrode.