Nanofibrous scaffold comprising usnic acid for skin tissue regeneration

Abstract

An example embodiment of the present disclosure relates to a nanofiber scaffold including polycaprolactone (poly(ε-caprolactone; PCL), decellularized extracellular matrix (dECM) and usnic acid (UA), and a preparation method thereof. The nanofiber scaffold of an example embodiment of the present disclosure has a uniform nanofiber structure, good fluid absorption and retention, moderate release rate, high mechanical stability, thermal stability, and semi-crystalline structure, and exhibits excellent antibacterial efficacy against fungi/bacteria such as Candida albicans, and good compatibility with human-derived fibroblasts.

Dependencies are inferred from the claim text.