Methods and compositions for treating sleep apnea
AssigneeThe Brigham and Women's Hospital, Inc.
InventorsD. Andrew Wellman, Luigi Taranto-Monternurro
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Abstract
Methods and compositions for the treatment of conditions associated with pharyngeal airway muscle collapse while the subject is in a non-fully conscious state, e.g., sleep apnea and snoring, comprising administration of a norepinephrine reuptake inhibitor (NRI) and a muscarinic receptor antagonist.
Claims46
A method of treating a subject having a condition associated with pharyngeal airway collapse while the subject is in a non-fully conscious state, the method comprising administering to a subject in need thereof an effective amount of (i) a norepinephrine reuptake inhibitor (NRI) and (ii) a muscarinic receptor antagonist.
A pharmaceutical composition comprising (i) a norepinephrine reuptake inhibitor (NRI), (ii) a muscarinic receptor antagonist and (iii), in a pharmaceutically acceptable carrier.
A norepinephrine reuptake inhibitor (NRI) and a muscarinic receptor antagonist, for use in treating a subject having a condition associated with pharyngeal airway collapse while the subject is in a non-fully conscious state.
A kit comprising a norepinephrine reuptake inhibitor (NRI) and a muscarinic receptor antagonist.
Dependencies are inferred from the claim text.